Nonetheless, hypoxia-induced stabilization of HIF is essential for intestinal homeostasis owing to its regulatory role in the transcription of barrier-protective genes, mucin secretion, antimicrobial peptide synthesis, nucleotide signaling, iron metabolism, and metabolic genes including hexokinase, lactate dehydrogenase, pyruvate kinase, aldolase, phosphofructokinase, and phosphoglycerate kinase, among others 73,80
The choice depends on the patients health, how bad the deficiency is, and the doctors advice
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Translational implications of the alcohol-metabolizing enzymes, including cytochrome P450-2E1, in alcoholic and nonalcoholic liver disease
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